chemotherapies for AML

I + A (I3A7, I2A5)

Idarubicin        mg (12mg/m2/day) in N/S 100 ml IV drip 30 mins QD on  D1 ~  D    

Cytarabine (Ara-C)       mg (100mg/m2/day) in N/S 500ml IV drip 24 hrs QD  on  D1 ~  D  

    5-HT3 antagonist iv(f) before C/T on D1~D__

HDAC

□ Idarubicin       mg(12mg/m2/day) in N/S 100 ml IV drip 30 mins QD on D1(   /   ),

□ D2(   /   ),

□ D3(   /   )

□ Mitoxantrone       mg (12mg/m2/day) in N/S 100 ml IV drip 30 mins QD on D1(   /   ),

□ D2(   /   ),

□ D3(   /   )

Cytarabine (Ara-C)       mg (2000mg/m2) in N/S 500ml IVD 3 hrs BID on

□ D1 PM~D5 AM (    /    PM ~    /    AM) 共8個doses

□ D1 AM~D4 PM (    /    PM ~    /    AM) 共8個doses

             Solu-medrol 40 mg IV before Ara-C bid on D1~D__ 

             5-HT3 antagonist iv(f) before C/T on D1~D__

FLAG

    □ Idarubicin      mg (10 mg/m2) in N/S 100 ml IV drip 30 mins QD

    [滴完後給Fludarabine]   on D1(   /   ), □ D2(   /   ), □ D3(   /   )

    □ Mitoxantrone       mg (10 mg/m2/day) in N/S 100 ml IV drip 30 mins QD

    [滴完後給Fludarabine] , on D1(   /   ),  □ D2(   /   ), □ D3(   /   )

    Fludarabine          mg (30mg/m2) in N/S 100 ml IV drip 30 mins QD

      on D1-D5 (   /   ~   /   )(50mg/vial,自費)

    Cytarabine (Ara-C)           mg (2000 mg/m2) in N/S 500ml IV drip 4 hrs QD on D1-D5

        [請於Fludarabine滴完3.5 hrs後再開始給Ara-C]

Pre-medication:

    G-CSF 300μg SC QN on D0-D6  ( 健保 / 自費 ), 12 hours before fludarabine

    ___________(5-HT3 antagonist) iv(f) before C/T on D1~D5 

    Solu-medrol (40 mg) 1 amp IV, before Ara-C QD on D1-D5

    Baktar____ # QD po (建議1~2# QD)

NEC

Mitoxantrone       mg (8mg/m2/day) in N/S 100ml IVD 30 mins qd on D1-D3 

Etoposide (VP-16)       mg (100mg/m2/day) in N/S 500ml IV drip 3hours qd on D1,3,5

Cytarabine (Ara-C)       mg (400mg/m2) in N/S 500ml IV drip 3 hrs q12h on 

            □ D1PM~D6AM (    /    PM ~    /    AM)

  □ D1AM~D5PM (    /    AM ~    /    PM)共10個doses

           Solu-Medrol 40mg IV q12h before Ara-C on D1~D_ 

           ___________(5-HT₃ antagonist) ivf before C/T on D1-5 (健保)

LDAC

Cytarabine (Ara-C) 40 mg in N/S 500 ml IVD 24 hrs qd on D1~D __

(一般使用7, 10, 或14天)

Idarubicin (for APL)

□ Idarubicin       mg (12mg/m2/day) in N/S 100 ml IV drip 30 mins QD on D1-D__

□ Idarubicin       mg (12mg/m2/day) in N/S 100 ml IV drip 30 mins QOD on D1, D3, D5, D7 

        ___________(5-HT3 antagonist) ivf before C/T on D1~D__ (健保)

Arsenic (for APL)

      Arsenic 10 mg in N/S 500ml IVD 2 hrs qd on D1~D28